Ulcerative oesophagitis in association with ulcerative colitis.

نویسندگان

  • C Rosendorff
  • N W Grieve
چکیده

Ulcerative colitis is primarily a disease of the large bowel, but a wide variety of extracolonic complications of the disease are now recognized (Edwards and Truelove, 1964), and a number of these occur in other parts of the alimentary tract. In the mouth, aphthous ulcers and monilial infections arise as a result of the general debility caused by the colitis (Grieve, 1964). Gastritis and small intestinal changes were found in a high proportion of patients with ulcerative colitis by Salem, Truelove, and Richards (1964), and are of more uncertain aetiology. It is possible that immunological factors, such as those described by Taylor (1965a and b), may play a part. In 1956, Berdal and Harnaes described two patients in whom dysphagia occurred during the course of a severe attack of ulcerative colitis. Both were found to have multiple ulcerations of the oesophagus, which eventually improved, leaving fibrous strictures. This paper records a similar occurrence in a young man suffering from ulcerative colitis. We can find no previous account of this complication in the British literature.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Serum Interleukin-23 Levels in Patients with Ulcerative Colitis

Background: Patients with ulcerative colitis are at increased risk of inflammation. Interleukin 23 (IL-23) is a newly identified cytokine with increased expression in inflamed biopsies of colon mucosa in patients with Crohn's disease; however, there is inconsistent evidence on its role in ulcerative colitis. Objective: We aimed to compare serum IL-23 level in patients with ulcerative colitis an...

متن کامل

بررسی فراوانی پلی مورفیسم C3435T ژن MDR1 در بیماران ایرانی مبتلا به کولیت اولسرو

Background: P-glycoprotein, the product of MDR1 (multi drug resistance) gene, is a trans membrane efflux pump, transferring drugs and toxins from intracellular to extracellular domains. It acts as a protective barrier to keep toxins out of the body by excreting them into the bile, urine and intestinal lumen. In the human gastrointestinal tract, P-glycoprotein is found in high concentrations on ...

متن کامل

Treatment of refractory ulcerative oesophagitis with omeprazole.

A 7 year old boy with ulcerative oesophagitis failed to respond to a two month course of intensive medical treatment using H2 receptor antagonist treatment in combination with domperidone and sucralfate. He demonstrated complete resolution using omeprazole 10 mg once a day for eight weeks.

متن کامل

IL-23 Receptor Gene rs7517847 and rs1004819 SNPs in Ulcerative Colitis

Background: Crohn’s disease (CD) and ulcerative colitis (UC) are two major clinical presentations of inflammatory bowel disease (IBD). Many novel candidate genes have been found to be associated with increased risk for IBD. Recently IL-23 receptor gene is identified as an IBD associated gene in genome-wide studies. Objective: To ascertain whether rs7517847 and rs1004819 SNPs in the IL-23 recept...

متن کامل

Interleukin-17 Serum Levels and TLR4 Polymorphisms in Ulcerative Colitis

Background: Inflammatory bowel disease, an autoimmune disease, has two clinical manifestations including Crohn’s disease and ulcerative colitis (UC). IL-17 has been the target of intensive research in autoimmune diseases. The influence of Toll like receptor 4 (TLR-4) gene polymorphisms on IL-17 production has also been revealed in UC patients and tissue inflammation in mice. Objectives: To inve...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Gut

دوره 8 4  شماره 

صفحات  -

تاریخ انتشار 1967